Price Difference between Generic and Branded Medicine Generic drugs usually cost you less than their brand-name versions. The price difference between generic and branded medicine is 80% to 80% due to a couple of factors, such as research cost and competition. Know why there is so much price difference between generic and branded medicine. Website: https://www.medexpressrx.com/health-wellness/generic-drugs-vs-branded-drugs-vs-bioequivalence-vs-biosimilars-vs-patented.aspx